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| 1st(1st leg) | AO Agia Napa | - | Anagennisi Derynias | 0:1 (0:0) | ||
| 2nd (2nd leg) | Anagennisi Derynias | - | AO Agia Napa | 0:3 (0:1) | ||
| 1st(1st leg): 09/01/2013 14:00 | 2nd (2nd leg): 16/01/2013 14:00 | Winner: AO Agia Napa | ||||
| 1st(1st leg) | Ermis Aradippou | - | Enosis Neon Paralimni | 0:1 (0:0) | ||
| 2nd (2nd leg) | Enosis Neon Paralimni | - | Ermis Aradippou | 0:0 (0:0) | ||
| 1st(1st leg): 09/01/2013 14:00 | 2nd (2nd leg): 16/01/2013 14:00 | Winner: Enosis Neon Paralimni | ||||
| 1st(1st leg) | AEL Limassol | - | APOEL Nikosia | 0:2 (0:0) | ||
| 2nd (2nd leg) | APOEL Nikosia | - | AEL Limassol | 1:3 (1:2) | ||
| 1st(1st leg): 09/01/2013 14:00 | 2nd (2nd leg): 23/01/2013 16:00 | Winner: AEL Limassol | ||||
| 1st(1st leg) | AE Paphos | - | PAEEK | 2:2 (1:1) | ||
| 2nd (2nd leg) | PAEEK | - | AE Paphos | 1:4 (1:1) | ||
| 1st(1st leg): 09/01/2013 14:00 | 2nd (2nd leg): 16/01/2013 14:00 | Winner: AE Paphos | ||||
| 1st(1st leg) | Ethnikos Achna | - | Omonia Nikosia | 0:2 (0:0) | ||
| 2nd (2nd leg) | Omonia Nikosia | - | Ethnikos Achna | 2:0 (0:0) | ||
| 1st(1st leg): 09/01/2013 16:00 | 2nd (2nd leg): 16/01/2013 16:00 | Winner: Omonia Nikosia | ||||
| 1st(1st leg) | Anorthosis Famagusta | - | Alki Larnaca | 1:1 (0:1) | ||
| 2nd (2nd leg) | Alki Larnaca | - | Anorthosis Famagusta | 1:2 (1:1, 1:1) aet | ||
| 1st(1st leg): 09/01/2013 16:00 | 2nd (2nd leg): 23/01/2013 14:00 | Winner: Anorthosis Famagusta | ||||
| 1st(1st leg) | AEK Larnaca | - | Olympiakos Nikosia | 1:0 (1:0) | ||
| 2nd (2nd leg) | Olympiakos Nikosia | - | AEK Larnaca | 3:3 (3:2) | ||
| 1st(1st leg): 09/01/2013 17:00 | 2nd (2nd leg): 30/01/2013 16:00 | Winner: AEK Larnaca | ||||
| 1st(1st leg) | Nea Salamina | - | Apollon Limassol | 0:1 (0:1) | ||
| 2nd (2nd leg) | Apollon Limassol | - | Nea Salamina | 1:0 (0:0) | ||
| 1st(1st leg): 23/01/2013 17:00 | 2nd (2nd leg): 30/01/2013 17:00 | Winner: Apollon Limassol | ||||
