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| 1st(1st leg) | Real Valladolid | - | Real Burgos | 1:1 | ||
| 2nd (2nd leg) | Real Burgos | - | Real Valladolid | 0:1 pso | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 06/01/1993 | Winner: Real Valladolid | ||||
| 1st(1st leg) | Xerez CD | - | Palamós CF | 0:1 | ||
| 2nd (2nd leg) | Palamós CF | - | Xerez CD | 5:4 pso | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 17/12/1992 | Winner: Palamós CF | ||||
| 1st(1st leg) | UD Las Palmas | - | SD Compostela | 2:2 | ||
| 2nd (2nd leg) | SD Compostela | - | UD Las Palmas | 2:1 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: SD Compostela | ||||
| 1st(1st leg) | FC Cartagena | - | Badajoz CF | 1:0 | ||
| 2nd (2nd leg) | Badajoz CF | - | FC Cartagena | 0:0 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 08/12/1992 | Winner: FC Cartagena | ||||
| 1st(1st leg) | Córdoba CF | - | CD Lugo | 1:1 | ||
| 2nd (2nd leg) | CD Lugo | - | Córdoba CF | 2:1 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: CD Lugo | ||||
| 1st(1st leg) | CD Ourense | - | UE Figueres | 1:0 | ||
| 2nd (2nd leg) | UE Figueres | - | CD Ourense | 2:0 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 17/12/1992 | Winner: UE Figueres | ||||
| 1st(1st leg) | Real Jaén | - | CD Logroñés | 0:0 | ||
| 2nd (2nd leg) | CD Logroñés | - | Real Jaén | 0:1 pso | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 17/12/1992 | Winner: Real Jaén | ||||
| 1st(1st leg) | RCD Mallorca | - | CD Castellón | 2:0 | ||
| 2nd (2nd leg) | CD Castellón | - | RCD Mallorca | 1:0 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: RCD Mallorca | ||||
| 1st(1st leg) | Racing Santander | - | Real Oviedo | 1:5 | ||
| 2nd (2nd leg) | Real Oviedo | - | Racing Santander | 3:2 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: Real Oviedo | ||||
| 1st(1st leg) | Atlético Marbella | - | CA Osasuna | 0:3 | ||
| 2nd (2nd leg) | CA Osasuna | - | Atlético Marbella | 4:1 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 15/12/1992 | Winner: CA Osasuna | ||||
| 1st(1st leg) | CF Gimnástico Alcázar | - | Sevilla FC | 0:2 | ||
| 2nd (2nd leg) | Sevilla FC | - | CF Gimnástico Alcázar | 5:0 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: Sevilla FC | ||||
| 1st(1st leg) | Villarreal CF | - | Espanyol Barcelona | 1:2 | ||
| 2nd (2nd leg) | Espanyol Barcelona | - | Villarreal CF | 1:5 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: Villarreal CF | ||||
| 1st(1st leg) | CF Extremadura | - | Cádiz CF | 5:1 | ||
| 2nd (2nd leg) | Cádiz CF | - | CF Extremadura | 0:1 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: CF Extremadura | ||||
| 1st(1st leg) | Barakaldo CF | - | CE Sabadell | 2:1 | ||
| 2nd (2nd leg) | CE Sabadell | - | Barakaldo CF | 4:1 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: CE Sabadell | ||||
| 1st(1st leg) | Benidorm CD | - | Real Betis | 2:2 | ||
| 2nd (2nd leg) | Real Betis | - | Benidorm CD | 2:1 | ||
| 1st(1st leg): 02/12/1992 | 2nd (2nd leg): 30/12/1992 | Winner: Real Betis | ||||
| 1st(1st leg) | CP Mérida | - | Deportivo La Coruña | 1:0 | ||
| 2nd (2nd leg) | Deportivo La Coruña | - | CP Mérida | 3:4 pso | ||
| 1st(1st leg): 08/12/1992 | 2nd (2nd leg): 06/01/1993 | Winner: CP Mérida | ||||
| 1st(1st leg) | FC Torrevieja | - | CD Tenerife | 1:0 | ||
| 2nd (2nd leg) | CD Tenerife | - | FC Torrevieja | 5:0 | ||
| 1st(1st leg): 08/12/1992 | 2nd (2nd leg): 17/12/1992 | Winner: CD Tenerife | ||||
| 1st(1st leg) | Rayo Vallecano | - | Sporting Gijón | 1:0 | ||
| 2nd (2nd leg) | Sporting Gijón | - | Rayo Vallecano | 4:1 | ||
| 1st(1st leg): 09/12/1992 | 2nd (2nd leg): 06/01/1993 | Winner: Sporting Gijón | ||||
| 1st(1st leg) | UD Realejos | - | Albacete | 1:3 | ||
| 2nd (2nd leg) | Albacete | - | UD Realejos | 2:0 | ||
| 1st(1st leg): 06/01/1993 | 2nd (2nd leg): 13/01/1993 | Winner: Albacete | ||||
