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| 1st(1st leg) | Vida | - | Motagua | 1:0 (0:0) | ||
| 2nd (2nd leg) | Motagua | - | Vida | 3:2 (1:0) | ||
| 1st(1st leg): 28/04/2011 02:30 | 2nd (2nd leg): 01/05/2011 02:30 | Winner: Vida | ||||
| 1st(1st leg) | Marathón | - | Olimpia | 1:0 (1:0) | ||
| 2nd (2nd leg) | Olimpia | - | Marathón | 1:0 (0:0) | ||
| 1st(1st leg): 29/04/2011 02:30 | 2nd (2nd leg): 02/05/2011 00:00 | |||||
