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| 01/10/2021 | 16:00 | FK Riteriai | - | Kauno Žalgiris | 0:0 (0:0) | |
| 02/10/2021 | 11:00 | FK Nevėžis | - | FC Džiugas | 1:1 (0:1) | |
| 13:00 | DFK Dainava | - | Hegelmann Litauen | 1:1 (1:1) | ||
| 03/10/2021 | 11:00 | FK Panevėžys | - | FK Sūduva | 1:1 (1:0) | |
| 13:00 | FK Banga Gargždai | - | FK Žalgiris | 0:3 (0:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Žalgiris | 31 | 19 | 9 | 3 | 66:24 | 42 | 66 |
| 2 |
|
FK Sūduva | 31 | 19 | 6 | 6 | 56:28 | 28 | 63 |
| 3 |
|
Kauno Žalgiris | 31 | 15 | 8 | 8 | 46:36 | 10 | 53 |
| 4 |
|
FK Panevėžys | 31 | 14 | 10 | 7 | 45:33 | 12 | 52 |
| 5 |
|
Hegelmann Litauen | 31 | 13 | 9 | 9 | 47:31 | 16 | 48 |
| 6 |
|
FK Riteriai | 31 | 9 | 13 | 9 | 41:34 | 7 | 40 |
| 7 |
|
FC Džiugas | 31 | 8 | 10 | 13 | 40:46 | -6 | 34 |
| 8 |
|
DFK Dainava | 31 | 8 | 9 | 14 | 36:50 | -14 | 30 |
| 9 |
|
FK Banga Gargždai | 31 | 7 | 4 | 20 | 33:68 | -35 | 25 |
| 10 |
|
FK Nevėžis | 31 | 2 | 4 | 25 | 13:73 | -60 | 10 |
| Champions League Quali. | |
| Relegation |
