 |
 |
|
| 21/10/2022 | 22:30 | Gallos Blancos | - | CF América | 0:1 (0:1) | |
| 23:00 | Pumas UNAM | - | Atlas Guadalajara | 3:2 (2:1) | ||
| 23/10/2022 | 18:00 | Puebla FC | - | FC Juárez | 0:3 (0:0) | |
| 24/10/2022 | 21:45 | Club León | - | Deportivo Toluca | 1:2 (1:2) | |
| 23:00 | Deportivo Guadalajara | - | Cruz Azul | 3:0 (2:0) | ||
| 23:00 | Club Necaxa | - | Atlético San Luis | 0:2 (0:1) | ||
| 25/10/2022 | 01:00 | UANL Tigres | - | Club Tijuana | 5:2 (2:2) | |
| 03:00 | Mazatlán FC | - | CF Pachuca | 3:1 (2:1) | ||
| 03:00 | Santos Laguna | - | CF Monterrey | 0:4 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportivo Guadalajara | 17 | 14 | 1 | 2 | 36:10 | 26 | 43 |
| 2 |
|
CF Monterrey | 17 | 13 | 3 | 1 | 46:16 | 30 | 42 |
| 3 |
|
UANL Tigres | 17 | 12 | 2 | 3 | 48:13 | 35 | 38 |
| 4 |
|
CF América | 17 | 11 | 3 | 3 | 37:16 | 21 | 36 |
| 5 |
|
Club Tijuana | 17 | 8 | 5 | 4 | 34:25 | 9 | 29 |
| 6 |
|
Deportivo Toluca | 17 | 8 | 2 | 7 | 27:29 | -2 | 26 |
| 7 |
|
CF Pachuca | 17 | 8 | 1 | 8 | 35:25 | 10 | 25 |
| 8 |
|
Cruz Azul | 17 | 7 | 4 | 6 | 16:16 | 0 | 25 |
| 9 |
|
Pumas UNAM | 17 | 7 | 3 | 7 | 30:36 | -6 | 24 |
| 10 |
|
Atlas Guadalajara | 17 | 6 | 5 | 6 | 25:25 | 0 | 23 |
| 11 |
|
FC Juárez | 17 | 7 | 1 | 9 | 24:28 | -4 | 22 |
| 12 |
|
Club León | 17 | 6 | 3 | 8 | 22:26 | -4 | 21 |
| 13 |
|
Atlético San Luis | 17 | 7 | 0 | 10 | 23:36 | -13 | 21 |
| 14 |
|
Santos Laguna | 17 | 6 | 1 | 10 | 24:36 | -12 | 19 |
| 15 |
|
Gallos Blancos | 17 | 3 | 3 | 11 | 16:31 | -15 | 12 |
| 16 |
|
Puebla FC | 17 | 3 | 2 | 12 | 20:38 | -18 | 11 |
| 17 |
|
Mazatlán FC | 17 | 3 | 2 | 12 | 15:49 | -34 | 11 |
| 18 |
|
Club Necaxa | 17 | 1 | 5 | 11 | 12:35 | -23 | 8 |
| Playoffs |
