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| 1st(1st leg) | Lobos BUAP | - | Club Necaxa | 3:0 | ||
| 2nd (2nd leg) | Club Necaxa | - | Lobos BUAP | 1:0 | ||
| 1st(1st leg): 25/04/2012 22:00 | 2nd (2nd leg): 29/04/2012 00:00 | Winner: Lobos BUAP | ||||
| 1st(1st leg) | Correcaminos UAT | - | Club León | 0:1 | ||
| 2nd (2nd leg) | Club León | - | Correcaminos UAT | 0:0 | ||
| 1st(1st leg): 26/04/2012 02:00 | 2nd (2nd leg): 29/04/2012 02:00 | Winner: Club León | ||||
