 |
 |
|
| 20/11/2021 | 21:00 | H&H Export Sébaco | - | Real Madriz | 2:3 (2:3) | |
| 21/11/2021 | 23:00 | Juventus Managua | - | UNAN Managua | 1:2 (1:1) | |
| 22/11/2021 | 00:00 | Diriangén FC | - | ART Municipal Jalapa | 5:0 (3:0) | |
| 00:00 | Real Estelí FC | - | Club Deportivo Ocotal | 4:0 (1:0) | ||
| 02:00 | Managua FC | - | CD Walter Ferretti | 3:1 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Real Estelí FC | 18 | 12 | 2 | 4 | 41:21 | 20 | 38 |
| 2 |
|
Diriangén FC | 18 | 12 | 2 | 4 | 38:20 | 18 | 38 |
| 3 |
|
Managua FC | 18 | 9 | 4 | 5 | 31:15 | 16 | 31 |
| 4 |
|
CD Walter Ferretti | 18 | 8 | 4 | 6 | 40:28 | 12 | 28 |
| 5 |
|
Club Deportivo Ocotal | 18 | 6 | 5 | 7 | 19:28 | -9 | 23 |
| 6 |
|
Juventus Managua | 18 | 6 | 4 | 8 | 21:27 | -6 | 22 |
| 7 |
|
Real Madriz | 18 | 6 | 3 | 9 | 24:32 | -8 | 21 |
| 8 |
|
H&H Export Sébaco | 18 | 4 | 6 | 8 | 26:33 | -7 | 18 |
| 9 |
|
UNAN Managua | 18 | 4 | 5 | 9 | 23:38 | -15 | 17 |
| 10 |
|
ART Municipal Jalapa | 18 | 3 | 5 | 10 | 12:33 | -21 | 14 |
| Next Round | |
| Qualification |
