1. Round | 08/07/2016 | Guaraní | - | Club Rubio Ñu | 1:0 | ||||
2. Round | 17/07/2016 | General Caballero ZC | - | Guaraní | 0:1 | ||||
3. Round | 20/07/2016 | Guaraní | - | River Plate | 2:0 | ||||
4. Round | 24/07/2016 | Deportivo Capiatá | - | Guaraní | 1:1 | ||||
5. Round | 31/07/2016 | Guaraní | - | Cerro Porteño | 0:2 | ||||
8. Round | 21/08/2016 | Libertad | - | Guaraní | 0:1 | ||||
13. Round | 01/10/2016 | Guaraní | - | General Caballero ZC | 2:1 | ||||
16. Round | 30/10/2016 | Cerro Porteño | - | Guaraní | 1:3 | ||||
19. Round | 27/11/2016 | Guaraní | - | Libertad | 1:3 | ||||
20. Round | 04/12/2016 | General Díaz | - | Guaraní | 1:2 |