4. Round | 06/08/2021 | FC Botoşani | - | UTA Arad | 2:1 | ||||
5. Round | 16/08/2021 | Gaz Metan Mediaş | - | FC Botoşani | 0:1 | ||||
6. Round | 22/08/2021 | FC Botoşani | - | Rapid Bucureşti | 0:2 | ||||
7. Round | 29/08/2021 | Sepsi OSK | - | FC Botoşani | 1:1 | ||||
9. Round | 19/09/2021 | Dinamo Bucureşti | - | FC Botoşani | 1:2 | ||||
10. Round | 26/09/2021 | FC Botoşani | - | FC Universitatea Craiova | 1:1 | ||||
12. Round | 18/10/2021 | FC Botoşani | - | Chindia Târgoviște | 0:0 | ||||
13. Round | 23/10/2021 | CS Mioveni | - | FC Botoşani | 1:1 | ||||
14. Round | 29/10/2021 | FC Botoşani | - | Farul Constanța | 0:2 | ||||
15. Round | 05/11/2021 | Argeș Pitești | - | FC Botoşani | 0:1 | ||||
16. Round | 21/11/2021 | FCSB | - | FC Botoşani | 3:1 | ||||
20. Round | 15/12/2021 | FC Botoşani | - | Gaz Metan Mediaş | 2:1 | ||||
21. Round | 18/12/2021 | Rapid Bucureşti | - | FC Botoşani | 1:1 | ||||
24. Round | 07/02/2022 | FC Botoşani | - | Dinamo Bucureşti | 4:0 | ||||
27. Round | 20/02/2022 | Chindia Târgoviște | - | FC Botoşani | 1:1 | ||||
28. Round | 27/02/2022 | FC Botoşani | - | CS Mioveni | 0:0 | ||||
29. Round | 03/03/2022 | Farul Constanța | - | FC Botoşani | 2:0 | ||||
30. Round | 07/03/2022 | FC Botoşani | - | Argeș Pitești | 1:2 |