2. Round | 01/08/2021 | Union Saint-Gilloise | - | Club Brugge KV | 0:1 | ||||
3. Round | 07/08/2021 | K Beerschot VA | - | Union Saint-Gilloise | 0:3 | ||||
5. Round | 22/08/2021 | KV Mechelen | - | Union Saint-Gilloise | 3:1 | ||||
6. Round | 28/08/2021 | Union Saint-Gilloise | - | Standard Liège | 4:0 | ||||
7. Round | 12/09/2021 | KRC Genk | - | Union Saint-Gilloise | 1:1 | ||||
8. Round | 18/09/2021 | Union Saint-Gilloise | - | SV Zulte Waregem | 2:1 | ||||
12. Round | 23/10/2021 | KAS Eupen | - | Union Saint-Gilloise | 2:3 | ||||
13. Round | 31/10/2021 | KAA Gent | - | Union Saint-Gilloise | 0:2 | ||||
14. Round | 06/11/2021 | Union Saint-Gilloise | - | Sporting Charleroi | 4:0 | ||||
16. Round | 26/11/2021 | Union Saint-Gilloise | - | Oud-Heverlee Leuven | 1:3 | ||||
18. Round | 12/12/2021 | Union Saint-Gilloise | - | KV Mechelen | 2:0 | ||||
19. Round | 15/12/2021 | SV Zulte Waregem | - | Union Saint-Gilloise | 0:2 | ||||
26. Round | 05/02/2022 | Royal Antwerp FC | - | Union Saint-Gilloise | 0:2 | ||||
28. Round | 19/02/2022 | Sporting Charleroi | - | Union Saint-Gilloise | 0:3 |