1. Round | 07/08/2021 | Bolton Wanderers | - | Milton Keynes Dons | 3:3 | ||||
2. Round | 14/08/2021 | Milton Keynes Dons | - | Sunderland AFC | 1:2 | ||||
3. Round | 17/08/2021 | Milton Keynes Dons | - | Charlton Athletic | 2:1 | ||||
4. Round | 21/08/2021 | Ipswich Town | - | Milton Keynes Dons | 2:2 | ||||
10. Round | 28/09/2021 | Milton Keynes Dons | - | Fleetwood Town | 3:3 | ||||
15. Round | 23/10/2021 | Milton Keynes Dons | - | Rotherham United | 0:3 | ||||
16. Round | 30/10/2021 | Crewe Alexandra | - | Milton Keynes Dons | 1:4 |