 |
 |
|
|
| 14/03/2022 | 18:30 | Royal Antwerp FC II | - | RSC Anderlecht II | 1:0 | |
| 18:30 | KRC Genk II | - | Oud-Heverlee Leuven II | 4:1 | ||
| 18:30 | Club NXT | - | SV Zulte Waregem II | 4:0 | ||
| 18:30 | KAA Gent II | - | Sporting Charleroi II | 2:1 | ||
| 18:30 | Cercle Brugge II | - | Standard Liège II | 1:3 | ||
| 19:00 | KV Mechelen II | - | Sint-Truidense VV II | 1:3 |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk II | 18 | 15 | 3 | 0 | 53:16 | 37 | 48 |
| 2 |
|
RSC Anderlecht II | 18 | 13 | 2 | 3 | 40:12 | 28 | 41 |
| 3 |
|
KAA Gent II | 18 | 10 | 4 | 4 | 35:22 | 13 | 34 |
| 4 |
|
Club NXT | 18 | 10 | 3 | 5 | 42:12 | 30 | 33 |
| 5 |
|
Standard Liège II | 18 | 9 | 4 | 5 | 28:23 | 5 | 31 |
| 6 |
|
Sint-Truidense VV II | 18 | 6 | 4 | 8 | 22:30 | -8 | 22 |
| 7 |
|
Sporting Charleroi II | 18 | 6 | 3 | 9 | 19:33 | -14 | 21 |
| 8 |
|
Oud-Heverlee Leuven II | 18 | 5 | 2 | 11 | 21:33 | -12 | 17 |
| 9 |
|
Royal Antwerp FC II | 18 | 4 | 3 | 11 | 21:38 | -17 | 15 |
| 10 |
|
SV Zulte Waregem II | 18 | 4 | 3 | 11 | 24:44 | -20 | 15 |
| 11 |
|
Cercle Brugge II | 18 | 3 | 5 | 10 | 21:33 | -12 | 14 |
| 12 |
|
KV Mechelen II | 18 | 3 | 4 | 11 | 13:43 | -30 | 13 |
| Relegation |
