1st(1st leg) Port Vale FC - Oxford United 0:2
2nd (2nd leg) Oxford United - Port Vale FC 0:0
1st(1st leg): 24/09/1990 2nd (2nd leg): 10/10/1990 Winner: Oxford United
1st(1st leg) AFC Bournemouth - Millwall FC 0:0
2nd (2nd leg) Millwall FC - AFC Bournemouth 2:1
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Millwall FC
1st(1st leg) Cardiff City - Portsmouth FC 1:1
2nd (2nd leg) Portsmouth FC - Cardiff City 3:1 aet
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Portsmouth FC
1st(1st leg) Carlisle United - Derby County 1:1
2nd (2nd leg) Derby County - Carlisle United 1:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Derby County
1st(1st leg) Chester City - Arsenal FC 0:1
2nd (2nd leg) Arsenal FC - Chester City 5:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Arsenal FC
1st(1st leg) Crystal Palace - Southend United 8:0
2nd (2nd leg) Southend United - Crystal Palace 1:2
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Crystal Palace
1st(1st leg) Darlington FC - Swindon Town 3:0
2nd (2nd leg) Swindon Town - Darlington FC 4:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Swindon Town
1st(1st leg) Hull City - Wolverhampton Wanderers 0:0
2nd (2nd leg) Wolverhampton Wanderers - Hull City 1:1 aet
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Hull City
1st(1st leg) Liverpool FC - Crewe Alexandra 5:1
2nd (2nd leg) Crewe Alexandra - Liverpool FC 1:4
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Liverpool FC
1st(1st leg) Luton Town - Bradford City 1:1
2nd (2nd leg) Bradford City - Luton Town 5:4 pso
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Bradford City
1st(1st leg) Middlesbrough FC - Newcastle United 2:0
2nd (2nd leg) Newcastle United - Middlesbrough FC 1:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Middlesbrough FC
1st(1st leg) Northampton Town - Sheffield United 0:1
2nd (2nd leg) Sheffield United - Northampton Town 2:1
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Sheffield United
1st(1st leg) Notts County - Oldham Athletic 1:0
2nd (2nd leg) Oldham Athletic - Notts County 5:2 aet
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Oldham Athletic
1st(1st leg) Plymouth Argyle - Wimbledon FC 1:0
2nd (2nd leg) Wimbledon FC - Plymouth Argyle 0:2
1st(1st leg): 25/09/1990 2nd (2nd leg): 10/10/1990 Winner: Plymouth Argyle
1st(1st leg) Rochdale AFC - Southampton FC 0:5
2nd (2nd leg) Southampton FC - Rochdale AFC 3:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Southampton FC
1st(1st leg) Rotherham United - Blackburn Rovers 1:1
2nd (2nd leg) Blackburn Rovers - Rotherham United 1:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Blackburn Rovers
1st(1st leg) Shrewsbury Town - Ipswich Town 1:1
2nd (2nd leg) Ipswich Town - Shrewsbury Town 3:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Ipswich Town
1st(1st leg) Sunderland AFC - Bristol City 0:1
2nd (2nd leg) Bristol City - Sunderland AFC 1:6
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Sunderland AFC
1st(1st leg) Wrexham AFC - Everton FC 0:5
2nd (2nd leg) Everton FC - Wrexham AFC 6:0
1st(1st leg): 25/09/1990 2nd (2nd leg): 09/10/1990 Winner: Everton FC
1st(1st leg) Aston Villa - Barnsley FC 1:0
2nd (2nd leg) Barnsley FC - Aston Villa 0:1
1st(1st leg): 26/09/1990 2nd (2nd leg): 09/10/1990 Winner: Aston Villa
1st(1st leg) Charlton Athletic - Leyton Orient 2:2
2nd (2nd leg) Leyton Orient - Charlton Athletic 1:0
1st(1st leg): 26/09/1990 2nd (2nd leg): 09/10/1990 Winner: Leyton Orient
1st(1st leg) Coventry City - Bolton Wanderers 4:2
2nd (2nd leg) Bolton Wanderers - Coventry City 2:3
1st(1st leg): 26/09/1990 2nd (2nd leg): 09/10/1990 Winner: Coventry City
1st(1st leg) Halifax Town - Manchester United 1:3
2nd (2nd leg) Manchester United - Halifax Town 2:1
1st(1st leg): 26/09/1990 2nd (2nd leg): 10/10/1990 Winner: Manchester United
1st(1st leg) Leicester City - Leeds United 1:0
2nd (2nd leg) Leeds United - Leicester City 3:0
1st(1st leg): 26/09/1990 2nd (2nd leg): 10/10/1990 Winner: Leeds United
1st(1st leg) Norwich City - Watford FC 2:0
2nd (2nd leg) Watford FC - Norwich City 0:3
1st(1st leg): 26/09/1990 2nd (2nd leg): 09/10/1990 Winner: Norwich City
1st(1st leg) Nottingham Forest - Burnley FC 4:1
2nd (2nd leg) Burnley FC - Nottingham Forest 0:1
1st(1st leg): 26/09/1990 2nd (2nd leg): 10/10/1990 Winner: Nottingham Forest
1st(1st leg) Queens Park Rangers - Peterborough United 3:1
2nd (2nd leg) Peterborough United - Queens Park Rangers 1:1
1st(1st leg): 26/09/1990 2nd (2nd leg): 09/10/1990 Winner: Queens Park Rangers
1st(1st leg) Sheffield Wednesday - Brentford FC 2:1
2nd (2nd leg) Brentford FC - Sheffield Wednesday 1:2
1st(1st leg): 26/09/1990 2nd (2nd leg): 09/10/1990 Winner: Sheffield Wednesday
1st(1st leg) Torquay United - Manchester City 0:4
2nd (2nd leg) Manchester City - Torquay United 0:0
1st(1st leg): 26/09/1990 2nd (2nd leg): 10/10/1990 Winner: Manchester City
1st(1st leg) Walsall FC - Chelsea FC 0:5
2nd (2nd leg) Chelsea FC - Walsall FC 4:1
1st(1st leg): 26/09/1990 2nd (2nd leg): 10/10/1990 Winner: Chelsea FC
1st(1st leg) West Ham United - Stoke City 3:0
2nd (2nd leg) Stoke City - West Ham United 1:2
1st(1st leg): 26/09/1990 2nd (2nd leg): 10/10/1990 Winner: West Ham United