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| 1st(1st leg) | Carmarthen Town | - | Port Talbot Town | 1:0 | ||
| 2nd (2nd leg) | Port Talbot Town | - | Carmarthen Town | 3:1 | ||
| 1st(1st leg): 20/01/2012 19:30 | 2nd (2nd leg): 14/02/2012 19:30 | Winner: Port Talbot Town | ||||
| 1st(1st leg) | Airbus UK | - | Bala Town | 4:1 | ||
| 2nd (2nd leg) | Bala Town | - | Airbus UK | 2:1 | ||
| 1st(1st leg): 20/01/2012 19:30 | 2nd (2nd leg): 07/02/2012 19:30 | Winner: Airbus UK | ||||
| 1st(1st leg) | Prestatyn Town | - | Newtown AFC | 1:1 | ||
| 2nd (2nd leg) | Newtown AFC | - | Prestatyn Town | 2:1 | ||
| 1st(1st leg): 21/01/2012 14:30 | 2nd (2nd leg): 15/02/2012 19:30 | Winner: Newtown AFC | ||||
| 1st(1st leg) | Afan Lido FC | - | Aberystwyth Town | 2:0 | ||
| 2nd (2nd leg) | Aberystwyth Town | - | Afan Lido FC | 1:0 | ||
| 1st(1st leg): 21/01/2012 15:45 | 2nd (2nd leg): 31/01/2012 19:30 | Winner: Afan Lido FC | ||||
