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| 1st(1st leg) | The New Saints | - | Airbus UK | 2:1 | ||
| 2nd (2nd leg) | Airbus UK | - | The New Saints | 0:1 | ||
| 1st(1st leg): 14/02/2012 19:30 | 2nd (2nd leg): 28/02/2012 19:30 | Winner: The New Saints | ||||
| 1st(1st leg) | Llanelli AFC | - | Neath FC | 0:0 | ||
| 2nd (2nd leg) | Neath FC | - | Llanelli AFC | 4:2 | ||
| 1st(1st leg): 15/02/2012 19:30 | 2nd (2nd leg): 28/02/2012 19:30 | Winner: Neath FC | ||||
| 1st(1st leg) | Port Talbot Town | - | Afan Lido FC | 0:2 | ||
| 2nd (2nd leg) | Afan Lido FC | - | Port Talbot Town | 0:0 | ||
| 1st(1st leg): 21/02/2012 19:30 | 2nd (2nd leg): 28/02/2012 19:30 | Winner: Afan Lido FC | ||||
| 1st(1st leg) | Bangor City | - | Newtown AFC | 1:1 | ||
| 2nd (2nd leg) | Newtown AFC | - | Bangor City | 5:1 | ||
| 1st(1st leg): 25/02/2012 13:30 | 2nd (2nd leg): 28/02/2012 19:30 | Winner: Newtown AFC | ||||
