Copa Libertadores   M. W D L goals
  at home 2 0 0 2 2 : 4
  Away 2 0 1 1 2 : 3
  4 0 1 3 4 : 7
Copa Sudamericana   M. W D L goals
  at home 1 0 1 0 1 : 1
  Away 1 0 0 1 0 : 2
  2 0 1 1 1 : 3
overall   M. W D L goals
  at home 3 0 1 2 3 : 5
  Away 3 0 1 2 2 : 5
  Neutral Place 0 0 0 0 0 : 0
  6 0 2 4 5 : 10
Copa Libertadores
2018 Group 1 Defensor Sporting - Cerro Porteño 0:1 (0:0)
2018 Group 1 Cerro Porteño - Defensor Sporting 2:1 (1:0)
1992 Group 5 Cerro Porteño - Defensor Sporting 1:1 (1:0)
1992 Group 5 Defensor Sporting - Cerro Porteño 2:3 (1:1)
Copa Sudamericana
2005 2. Round Defensor Sporting - Cerro Porteño 1:1 (0:1)
2005 2. Round Cerro Porteño - Defensor Sporting 2:0 (1:0)

For games that were decided on penalties the score after 120 minutes will be included in the ranking