| Period | Manager | Country | born |
| 01/01/2023 - 31/12/2024 | Francisco Palladino |
|
23/01/1983 |
| 26/04/2022 - 31/12/2022 | Miguel Ponce |
|
19/08/1971 |
| 07/04/2022 - 24/04/2022 | John Valladares |
|
24/03/1980 |
| 08/11/2021 - 05/04/2022 | Jorge Garcés |
|
13/05/1954 |
| 08/11/2021 - 10/11/2021 | Domingo Sorace |
|
|
| 01/07/2021 - 07/11/2021 | Emiliano Astorga |
|
21/09/1960 |
| 13/05/2021 - 30/06/2021 | Víctor Rivero |
|
15/03/1980 |
| 18/02/2021 - 09/05/2021 | Ronald Fuentes |
|
22/06/1969 |
| 03/08/2018 - 28/02/2021 | Miguel Ramírez |
|
11/06/1970 |
| 22/03/2018 - 26/07/2018 | Moisés Villarroel |
|
12/02/1976 |
| 01/07/2017 - 19/03/2018 | Nicolás Córdova |
|
09/02/1979 |
| 01/07/2016 - 30/06/2017 | Eduardo Espinel |
|
28/06/1972 |
| 01/01/2016 - 30/06/2016 | Alfredo Arias |
|
28/11/1958 |
| 01/07/2014 - 31/12/2015 | Emiliano Astorga |
|
21/09/1960 |
| 04/03/2014 - 30/06/2014 | Héctor Robles |
|
07/09/1971 |
| 20/08/2012 - 03/03/2014 | Ivo Basay |
|
13/04/1966 |
| 13/08/2012 - 19/08/2012 | Héctor Robles |
|
07/09/1971 |
| 01/01/2012 - 13/08/2012 | Arturo Salah |
|
04/12/1949 |
| 03/08/2011 - 31/12/2011 | Héctor Robles |
|
07/09/1971 |
| 01/01/2011 - 02/08/2011 | Juan Llop |
|
01/06/1963 |
| 01/01/2010 - 31/12/2010 | Jorge Garcés |
|
13/05/1954 |
| 01/01/2009 - 31/12/2010 | Humberto Zuccarelli |
|
18/03/1948 |
| 01/01/2008 - 30/06/2008 | Gustavo Huerta |
|
15/10/1957 |
| 01/01/2006 - 31/12/2007 | Hernán Godoy |
|
14/05/1941 |
| 01/07/2005 - 30/06/2006 | Mario Soto |
|
10/07/1950 |
| 01/01/2002 - 31/12/2002 | Ricardo Dabrowski |
|
28/03/1961 |
| 01/07/1999 - 30/06/2001 | Jorge Garcés |
|
13/05/1954 |
| 01/07/1991 - 31/12/1991 | Hernán Godoy |
|
14/05/1941 |
| 01/07/1990 - 30/06/1991 | Oscar Blanco |
|
20/11/1948 |
| 01/01/1971 - 31/12/1971 | Luis Alamos |
|
25/12/1923 |
| 01/01/1969 - 31/12/1969 | Donato Hernández |
|
12/12/1923 |
![Santiago Wanderers [U20]](https://s.hs-data.com/bilder/wappen/mini/29333.gif?fallback=png "Santiago Wanderers [U20]"){kind=small}
![Santiago Wanderers [U17]](https://s.hs-data.com/bilder/wappen/mini/29802.gif?fallback=png "Santiago Wanderers [U17]"){kind=small}