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| 11/01/2012 | 12:00 | AO Kerkyra | - | Doxa Dramas FC | 2:0 (2:0) | |
| 14:00 | PAS Giannina | - | Asteras Tripolis | 1:4 (0:0) | ||
| 17:00 | Olympiakos Piraeus | - | Thrasyvoulos Fylis | 3:0 (2:0) | ||
| 19:00 | Panionios GSS | - | Panathinaikos | 4:3 (0:0, 0:0, 0:0) pso | ||
| 12/01/2012 | 18:00 | Atromitos | - | Aris Saloniki | 2:1 (0:0) | |
| 17/01/2012 | 16:00 | Skoda Xanthi | - | Panserraikos | 1:2 (1:1) | |
| 18/01/2012 | 18:00 | PAOK Saloniki | - | AEK Athen | 2:0 (1:0) | |
| 19/01/2012 | 16:00 | Panetolikos | - | OFI Heraklion | 1:3 (1:1) |
