Championship   M. W D L goals
  at home 6 3 2 1 11 : 4
  Away 6 2 3 1 6 : 6
  12 5 5 2 17 : 10
FA Cup   M. W D L goals
  at home 1 1 0 0 3 : 0
  Away 1 1 0 0 3 : 1
  2 2 0 0 6 : 1
League One   M. W D L goals
  at home 5 2 3 0 6 : 3
  Away 5 1 2 2 5 : 7
  10 3 5 2 11 : 10
League Two   M. W D L goals
  at home 2 1 0 1 3 : 2
  Away 2 1 0 1 2 : 1
  4 2 0 2 5 : 3
overall   M. W D L goals
  at home 14 7 5 2 23 : 9
  Away 14 5 5 4 16 : 15
  Neutral Place 0 0 0 0 0 : 0
  28 12 10 6 39 : 24
Championship
1996/1997 40. Round Tranmere Rovers - Southend United 3:0 (3:0)
1996/1997 1. Round Southend United - Tranmere Rovers 1:1 (1:1)
1995/1996 39. Round Southend United - Tranmere Rovers 2:0
1995/1996 13. Round Tranmere Rovers - Southend United 3:0
1994/1995 9. Round Tranmere Rovers - Southend United 0:2
1994/1995 6. Round Southend United - Tranmere Rovers 0:0
1993/1994 8. Round Tranmere Rovers - Southend United 1:1
1993/1994 3. Round Southend United - Tranmere Rovers 1:2
1992/1993 8. Round Southend United - Tranmere Rovers 1:2
1992/1993 4. Round Tranmere Rovers - Southend United 3:0
1991/1992 9. Round Southend United - Tranmere Rovers 1:1
1991/1992 3. Round Tranmere Rovers - Southend United 1:1
FA Cup
2001/2002 3. Round Southend United - Tranmere Rovers 1:3 (0:0)
1933/1934 3. Round Tranmere Rovers - Southend United 3:0
League One
2019/2020 27. Round Southend United - Tranmere Rovers 0:0 (0:0)
2019/2020 14. Round Tranmere Rovers - Southend United 1:1 (0:1)
2009/2010 31. Round Southend United - Tranmere Rovers 1:1 (1:0)
2009/2010 18. Round Tranmere Rovers - Southend United 2:0 (1:0)
2008/2009 32. Round Southend United - Tranmere Rovers 2:1 (1:0)
2008/2009 16. Round Tranmere Rovers - Southend United 2:2 (2:2)
2007/2008 45. Round Tranmere Rovers - Southend United 1:0 (0:0)
2007/2008 10. Round Southend United - Tranmere Rovers 1:2 (1:1)
2005/2006 29. Round Tranmere Rovers - Southend United 0:0 (0:0)
2005/2006 9. Round Southend United - Tranmere Rovers 3:1 (2:0)
League Two
2020/2021 35. Round Southend United - Tranmere Rovers 0:2 (0:2)
2020/2021 8. Round Tranmere Rovers - Southend United 2:0 (1:0)
2014/2015 42. Round Southend United - Tranmere Rovers 1:0 (1:0)
2014/2015 18. Round Tranmere Rovers - Southend United 1:2 (0:2)

For games that were decided on penalties the score after 120 minutes will be included in the ranking