| 11. Round | 05/11/1950 | Rot-Weiß Oberhausen | - | FC Schalke 04 | 0:1 | ||||
| 18. Round | 21/01/1951 | SF Hamborn 07 | - | FC Schalke 04 | 4:0 | ||||
| 21. Round | 11/02/1951 | FC Schalke 04 | - | Rot-Weiss Essen | 3:0 | ||||
| 22. Round | 18/02/1951 | SpVgg Erkenschwick | - | FC Schalke 04 | 1:1 | ||||
| 23. Round | 25/02/1951 | FC Schalke 04 | - | Preußen Dellbrück | 8:1 | ||||
| 24. Round | 04/03/1951 | FC Schalke 04 | - | Fortuna Düsseldorf | 1:0 | ||||
| 25. Round | 11/03/1951 | Duisburger SpV | - | FC Schalke 04 | 2:2 | ||||
| 26. Round | 23/03/1951 | FC Schalke 04 | - | Rot-Weiß Oberhausen | 1:1 | ||||
| 27. Round | 01/04/1951 | Rheydter SV | - | FC Schalke 04 | 0:1 | ||||
| 28. Round | 08/04/1951 | 1. FC Köln | - | FC Schalke 04 | 2:0 | ||||
| 29. Round | 22/04/1951 | FC Schalke 04 | - | Borussia Dortmund | 0:0 | ||||
| 30. Round | 29/04/1951 | DJK SF Katernberg | - | FC Schalke 04 | 1:4 |  |
Germany