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| 1st(1st leg) | Sporting CP | - | CD Fátima | 1:2 | ||
| 2nd (2nd leg) | CD Fátima | - | Sporting CP | 2:3 | ||
| 1st(1st leg): 20/10/2007 19:00 | 2nd (2nd leg): 31/10/2007 19:45 | Winner: Sporting CP | ||||
| 1st(1st leg) | SL Benfica | - | Vitória Setúbal | 1:1 | ||
| 2nd (2nd leg) | Vitória Setúbal | - | SL Benfica | 2:1 | ||
| 1st(1st leg): 20/10/2007 21:00 | 2nd (2nd leg): 31/10/2007 01:01 | Winner: Vitória Setúbal | ||||
| 1st(1st leg) | Portimonense SC | - | SC Beira-Mar | 1:0 | ||
| 2nd (2nd leg) | SC Beira-Mar | - | Portimonense SC | 3:1 | ||
| 1st(1st leg): 21/10/2007 16:00 | 2nd (2nd leg): 31/10/2007 20:00 | Winner: SC Beira-Mar | ||||
| 1st(1st leg) | FC Penafiel | - | União Leiria | 3:1 | ||
| 2nd (2nd leg) | União Leiria | - | FC Penafiel | 1:0 | ||
| 1st(1st leg): 21/10/2007 16:00 | 2nd (2nd leg): 31/10/2007 20:45 | Winner: FC Penafiel | ||||
