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| 1st(1st leg) | 1. FC Köln | - | Bor. Mönchengladbach | 0:0 (0:0) | ||
| 2nd (2nd leg) | Bor. Mönchengladbach | - | 1. FC Köln | 5:0 (2:0) | ||
| 1st(1st leg): 28/11/1972 19:00 | 2nd (2nd leg): 13/12/1972 19:00 | Winner: Bor. Mönchengladbach | ||||
| 1st(1st leg) | OFK Beograd | - | PFC Beroe | 0:0 (0:0) | ||
| 2nd (2nd leg) | PFC Beroe | - | OFK Beograd | 1:3 (1:0) | ||
| 1st(1st leg): 29/11/1972 12:30 | 2nd (2nd leg): 13/12/1972 12:00 | Winner: OFK Beograd | ||||
| 1st(1st leg) | FC Ararat | - | 1. FC Kaiserslautern | 2:0 (1:0) | ||
| 2nd (2nd leg) | 1. FC Kaiserslautern | - | FC Ararat | 5:4 (1:0, 2:0, 2:0) pso | ||
| 1st(1st leg): 29/11/1972 15:00 | 2nd (2nd leg): 13/12/1972 19:00 | Winner: 1. FC Kaiserslautern | ||||
| 1st(1st leg) | BFC Dynamo | - | Liverpool FC | 0:0 (0:0) | ||
| 2nd (2nd leg) | Liverpool FC | - | BFC Dynamo | 3:1 (2:1) | ||
| 1st(1st leg): 29/11/1972 18:30 | 2nd (2nd leg): 13/12/1972 19:30 | Winner: Liverpool FC | ||||
| 1st(1st leg) | FC Twente '65 | - | UD Las Palmas | 3:0 (2:0) | ||
| 2nd (2nd leg) | UD Las Palmas | - | FC Twente '65 | 2:1 (1:0) | ||
| 1st(1st leg): 29/11/1972 19:00 | 2nd (2nd leg): 13/12/1972 19:30 | Winner: FC Twente '65 | ||||
| 1st(1st leg) | Tottenham Hotspur | - | Crvena Zvezda | 2:0 (1:0) | ||
| 2nd (2nd leg) | Crvena Zvezda | - | Tottenham Hotspur | 1:0 (0:0) | ||
| 1st(1st leg): 29/11/1972 19:30 | 2nd (2nd leg): 13/12/1972 15:00 | Winner: Tottenham Hotspur | ||||
| 1st(1st leg) | FC Porto | - | Dynamo Dresden | 1:2 (0:1) | ||
| 2nd (2nd leg) | Dynamo Dresden | - | FC Porto | 1:0 (0:0) | ||
| 1st(1st leg): 29/11/1972 21:45 | 2nd (2nd leg): 13/12/1972 19:00 | Winner: Dynamo Dresden | ||||
| 1st(1st leg) | Vitória Setúbal | - | Inter | 2:0 (1:0) | ||
| 2nd (2nd leg) | Inter | - | Vitória Setúbal | 1:0 (1:0) | ||
| 1st(1st leg): 29/11/1972 21:45 | 2nd (2nd leg): 13/12/1972 12:00 | Winner: Vitória Setúbal | ||||
