20. Round
25/09/2021 12:00 FK Qo’qon 1912 FK Qo’qon 1912 - Andijon PFK Andijon PFK 1:1 (0:0)
25/09/2021 14:30 Pakhtakor Tashkent Pakhtakor Tashkent - FK Turon FK Turon 3:1
26/09/2021 12:15 So’g’diyona PFK So’g’diyona PFK - Metallurg Bekobod Metallurg Bekobod 2:0 (1:0)
26/09/2021 14:30 FC AGMK FC AGMK - Surkhon Termez FK Surkhon Termez FK 1:0 (0:0)
26/09/2021 14:30 Navbahor Namangan Navbahor Namangan - Qizilqum Zarafshon Qizilqum Zarafshon 0:0 (0:0)
27/09/2021 15:00 Lokomotiv Tashkent Lokomotiv Tashkent - FK Mash'al Mubarek FK Mash'al Mubarek 2:1 (0:1)
27/09/2021 15:00 Nasaf Qarshi Nasaf Qarshi - Bunyodkor PFK Bunyodkor PFK 5:0 (2:0)
21. Round
01/10/2021 FK Qo’qon 1912 FK Qo’qon 1912 - Pakhtakor Tashkent Pakhtakor Tashkent -:-
01/10/2021 Metallurg Bekobod Metallurg Bekobod - Lokomotiv Tashkent Lokomotiv Tashkent -:-
02/10/2021 Andijon PFK Andijon PFK - So’g’diyona PFK So’g’diyona PFK -:-
02/10/2021 Bunyodkor PFK Bunyodkor PFK - FC AGMK FC AGMK -:-
02/10/2021 FK Mash'al Mubarek FK Mash'al Mubarek - Nasaf Qarshi Nasaf Qarshi -:-
03/10/2021 Qizilqum Zarafshon Qizilqum Zarafshon - FK Turon FK Turon -:-
03/10/2021 Surkhon Termez FK Surkhon Termez FK - Navbahor Namangan Navbahor Namangan -:-