11. Round
23/10/2021 13:00 KF Shkupi KF Shkupi - FK Renova FK Renova -:-
24/10/2021 13:00 FK Borec FK Borec - Akademija Pandev Akademija Pandev -:-
24/10/2021 13:00 FK Pelister FK Pelister - FK Bregalnica Štip FK Bregalnica Štip -:-
24/10/2021 13:00 FK Skopje FK Skopje - GFK Tikveš GFK Tikveš -:-
24/10/2021 13:00 KF Shkëndija 79 KF Shkëndija 79 - FK Rabotnički FK Rabotnički -:-
24/10/2021 13:00 Makedonija GP Makedonija GP - FC Struga FC Struga -:-
12. Round
31/10/2021 12:00 FK Borec FK Borec - FK Rabotnički FK Rabotnički -:-
31/10/2021 12:00 FK Pelister FK Pelister - Makedonija GP Makedonija GP -:-
31/10/2021 12:00 KF Shkupi KF Shkupi - FK Bregalnica Štip FK Bregalnica Štip -:-
31/10/2021 12:00 FK Skopje FK Skopje - FK Renova FK Renova -:-
31/10/2021 12:00 KF Shkëndija 79 KF Shkëndija 79 - GFK Tikveš GFK Tikveš -:-
31/10/2021 12:00 FC Struga FC Struga - Akademija Pandev Akademija Pandev -:-
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