| 8. Round | 20/10/2017 | Norwich City U23 | - | Southampton FC U23 | 3:0 | ||||
| 16. Round | 29/01/2018 | Stoke City U23 | - | Southampton FC U23 | 0:2 | ||||
| 17. Round | 05/02/2018 | Southampton FC U23 | - | West Bromwich Albion U23 | 3:2 |  |
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| 18. Round | 19/02/2018 | Newcastle United U23 | - | Southampton FC U23 | 1:5 | ||||
| 19. Round | 05/03/2018 | Brighton & Hove Albion U23 | - | Southampton FC U23 | 1:1 | ||||
| 20. Round | 12/03/2018 | Southampton FC U23 | - | Norwich City U23 | 2:1 | |
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| 14. Round | 20/03/2018 | Blackburn Rovers U23 | - | Southampton FC U23 | 1:0 | ||||
| 21. Round | 13/04/2018 | Fulham FC U23 | - | Southampton FC U23 | 0:2 | ||||
| 22. Round | 23/04/2018 | Southampton FC U23 | - | Middlesbrough FC U23 | 2:1 |
Ireland