| 8. Round | 10/02/2022 | National Bank SC | - | Smouha Sporting Club | 1:2 | ||||
| 9. Round | 15/02/2022 | Smouha Sporting Club | - | Zamalek | 2:0 | ||||
| 10. Round | 21/02/2022 | Al Mokawloon | - | Smouha Sporting Club | 0:0 | ||||
| 13. Round | 15/03/2022 | Future FC | - | Smouha Sporting Club | 4:0 | ||||
| 15. Round | 20/04/2022 | El Gouna | - | Smouha Sporting Club | 1:0 | ||||
| 22. Round | 17/06/2022 | Tala'ea El Gaish SC | - | Smouha Sporting Club | 3:3 | ||||
| 23. Round | 29/06/2022 | Smouha Sporting Club | - | Al Ahly SC | 3:2 | ||||
| 26. Round | 24/07/2022 | Zamalek | - | Smouha Sporting Club | 2:0 |
Nigeria