1. Round | 15/08/2021 | FC Utrecht | - | Sparta Rotterdam | 4:0 | ||||
2. Round | 21/08/2021 | FC Groningen | - | FC Utrecht | 0:0 | ||||
4. Round | 11/09/2021 | FC Twente | - | FC Utrecht | 1:0 | ||||
5. Round | 18/09/2021 | FC Utrecht | - | RKC Waalwijk | 2:2 | ||||
7. Round | 25/09/2021 | FC Utrecht | - | PEC Zwolle | 5:1 | ||||
14. Round | 28/11/2021 | FC Utrecht | - | Heracles Almelo | 1:0 | ||||
15. Round | 04/12/2021 | PSV Eindhoven | - | FC Utrecht | 4:1 | ||||
16. Round | 11/12/2021 | FC Utrecht | - | Go Ahead Eagles | 0:0 | ||||
17. Round | 18/12/2021 | Fortuna Sittard | - | FC Utrecht | 2:2 |