| 5. Round | 27/09/2020 | FC Politehnica Iași | - | FCSB | 5:2 | ||||
| 6. Round | 03/10/2020 | FCSB | - | Dinamo Bucureşti | 3:2 | ||||
| 8. Round | 26/10/2020 | FCSB | - | FC Hermannstadt | 5:0 | ||||
| 9. Round | 02/11/2020 | Chindia Târgoviște | - | FCSB | 0:2 | ||||
| 10. Round | 07/11/2020 | FCSB | - | FC Botoşani | 4:1 |  |
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| 12. Round | 05/12/2020 | FCSB | - | UTA Arad | 3:0 | ||||
| 16. Round | 15/01/2021 | FCSB | - | Astra Giurgiu | 3:0 | ||||
| 17. Round | 19/01/2021 | FC Viitorul Constanța | - | FCSB | 2:2 | ||||
| 18. Round | 22/01/2021 | FCSB | - | FC Voluntari | 2:1 | |
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| 19. Round | 26/01/2021 | Argeș Pitești | - | FCSB | 0:0 | |
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| 20. Round | 30/01/2021 | FCSB | - | FC Politehnica Iași | 3:1 | ||||
| 21. Round | 03/02/2021 | Dinamo Bucureşti | - | FCSB | 0:1 | |
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| 23. Round | 14/02/2021 | FC Hermannstadt | - | FCSB | 1:0 | ||||
| 24. Round | 20/02/2021 | FCSB | - | Chindia Târgoviște | 1:0 | ||||
| 25. Round | 28/02/2021 | FC Botoşani | - | FCSB | 0:2 | ||||
| 26. Round | 07/03/2021 | FCSB | - | Gaz Metan Mediaş | 1:0 | |
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| 28. Round | 19/03/2021 | FCSB | - | CFR Cluj | 3:0 | ||||
| 29. Round | 04/04/2021 | FCSB | - | CS Universitatea Craiova | 0:0 | ||||
| 30. Round | 10/04/2021 | Sepsi OSK | - | FCSB | 1:1 |
Romania