| 1. Round | 25/10/2021 | Smouha Sporting Club | - | Ittihad El Iskandary | 4:4 | ||||
| 2. Round | 30/10/2021 | Ittihad El Iskandary | - | Future FC | 3:2 | ||||
| 3. Round | 04/11/2021 | Pyramids FC | - | Ittihad El Iskandary | 3:0 | ||||
| 4. Round | 18/11/2021 | Ittihad El Iskandary | - | El Gouna | 1:0 | ||||
| 5. Round | 21/11/2021 | Misr lel-Maqasah SC | - | Ittihad El Iskandary | 0:0 | ||||
| 6. Round | 25/11/2021 | Ittihad El Iskandary | - | Pharco FC | 1:2 | ||||
| 7. Round | 20/12/2021 | Ittihad El Iskandary | - | Ceramica Cleopatra | 4:4 |
Egypt