| 7. Round | 10/01/2021 | US Ben Guerdane | - | CS Sfaxien | 1:0 |  |
|||
| 8. Round | 13/01/2021 | CS Sfaxien | - | Espérance de Tunis | 2:0 | ||||
| 9. Round | 23/01/2021 | CA Bizertin | - | CS Sfaxien | 1:1 | ||||
| 10. Round | 26/01/2021 | CS Sfaxien | - | ES Métlaoui | 2:1 | ||||
| 12. Round | 03/02/2021 | JS Kairouan | - | CS Sfaxien | 0:4 |  |
|||
| 13. Round | 07/02/2021 | CS Sfaxien | - | AS Rejiche | 1:0 | |
|||
| 4. Round | 16/02/2021 | Olympique Béja | - | CS Sfaxien | 1:0 | |
|||
| 15. Round | 04/03/2021 | CS Sfaxien | - | US Tataouine | 1:2 | |
|||
| 16. Round | 07/03/2021 | Club Africain | - | CS Sfaxien | 0:0 | ||||
| 18. Round | 13/03/2021 | Stade Tunisien | - | CS Sfaxien | 1:0 | ||||
| 20. Round | 21/03/2021 | CS Sfaxien | - | US Ben Guerdane | 1:1 | |
|||
| 14. Round | 24/03/2021 | US Monastir | - | CS Sfaxien | 0:0 | ||||
| 23. Round | 07/04/2021 | ES Métlaoui | - | CS Sfaxien | 0:1 | ||||
| 24. Round | 05/05/2021 | CS Sfaxien | - | AS Soliman | 0:1 | ||||
| 25. Round | 09/05/2021 | CS Sfaxien | - | JS Kairouan | 2:0 | |
Tunisia