| 1. Round | 21/10/2015 | Zamalek | - | Wadi Degla SC | 2:0 | ||||
| 2. Round | 25/10/2015 | Aswan SC | - | Zamalek | 0:0 | ||||
| 3. Round | 31/10/2015 | Zamalek | - | El Entag El Harby | 2:1 | ||||
| 4. Round | 04/11/2015 | Al Mokawloon | - | Zamalek | 1:2 |  |
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| 9. Round | 20/12/2015 | Tala'ea El Gaish SC | - | Zamalek | 3:2 | ||||
| 10. Round | 23/12/2015 | Zamalek | - | Ghazl Al Mehalla | 5:0 | ||||
| 12. Round | 02/01/2016 | Zamalek | - | Misr lel-Maqasah SC | 2:2 | ||||
| 5. Round | 05/01/2016 | Zamalek | - | el Dakhleya SC | 2:0 | ||||
| 13. Round | 09/01/2016 | ENPPI | - | Zamalek | 0:1 | ||||
| 14. Round | 16/01/2016 | Zamalek | - | Ittihad El Shorta | 1:0 | ||||
| 15. Round | 20/01/2016 | Al Masry Club | - | Zamalek | 0:1 | ||||
| 16. Round | 24/01/2016 | Zamalek | - | Smouha Sporting Club | 1:1 | ||||
| 17. Round | 09/02/2016 | Al Ahly SC | - | Zamalek | 2:0 | ||||
| 18. Round | 14/02/2016 | Wadi Degla SC | - | Zamalek | 1:1 | ||||
| 19. Round | 18/02/2016 | Zamalek | - | Aswan SC | 1:0 | ||||
| 7. Round | 22/02/2016 | Zamalek | - | Ittihad El Iskandary | 2:1 | ||||
| 22. Round | 14/04/2016 | el Dakhleya SC | - | Zamalek | 0:0 | ||||
| 32. Round | 24/06/2016 | Zamalek | - | Al Masry Club | 2:2 |  |
Egypt