| 1. Round | 28/10/2021 | Ghazl Al Mehalla | - | Al Masry Club | 1:1 | ||||
| 2. Round | 01/11/2021 | El Sharkia Lel Dokhan | - | Ghazl Al Mehalla | 2:3 |  |
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| 3. Round | 05/11/2021 | Ghazl Al Mehalla | - | ENPPI | 3:0 | |
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| 4. Round | 19/11/2021 | Tala'ea El Gaish SC | - | Ghazl Al Mehalla | 0:0 | ||||
| 5. Round | 22/11/2021 | Ghazl Al Mehalla | - | Al Ahly SC | 2:3 | ||||
| 6. Round | 26/11/2021 | Ismaily | - | Ghazl Al Mehalla | 0:0 | ||||
| 7. Round | 20/12/2021 | Ghazl Al Mehalla | - | National Bank SC | 1:1 | ||||
| 9. Round | 15/02/2022 | Ghazl Al Mehalla | - | Al Mokawloon | 1:1 | ||||
| 12. Round | 09/03/2022 | Ghazl Al Mehalla | - | Future FC | 0:0 | ||||
| 13. Round | 09/04/2022 | Pyramids FC | - | Ghazl Al Mehalla | 1:0 | ||||
| 15. Round | 18/04/2022 | Misr lel-Maqasah SC | - | Ghazl Al Mehalla | 0:1 | ||||
| 16. Round | 25/04/2022 | Ghazl Al Mehalla | - | Pharco FC | 1:1 | ||||
| 18. Round | 11/05/2022 | Al Masry Club | - | Ghazl Al Mehalla | 1:1 | |
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| 19. Round | 16/05/2022 | Ghazl Al Mehalla | - | El Sharkia Lel Dokhan | 1:0 | ||||
| 20. Round | 24/05/2022 | ENPPI | - | Ghazl Al Mehalla | 2:2 | ||||
| 21. Round | 28/05/2022 | Ghazl Al Mehalla | - | Tala'ea El Gaish SC | 0:1 |
Egypt