| 1. Round | 28/10/2021 | Ghazl Al Mehalla | - | Al Masry Club | 1:1 | ||||
| 2. Round | 01/11/2021 | Al Masry Club | - | Smouha Sporting Club | 0:0 | ||||
| 3. Round | 05/11/2021 | Future FC | - | Al Masry Club | 1:1 | ||||
| 4. Round | 19/11/2021 | Al Masry Club | - | Pyramids FC | 2:2 | ||||
| 5. Round | 22/11/2021 | El Gouna | - | Al Masry Club | 0:3 | ||||
| 11. Round | 03/03/2022 | Al Masry Club | - | ENPPI | 2:2 | ||||
| 12. Round | 09/03/2022 | Tala'ea El Gaish SC | - | Al Masry Club | 1:0 | ||||
| 13. Round | 09/04/2022 | Al Masry Club | - | Al Ahly SC | 1:0 | ||||
| 16. Round | 28/04/2022 | Zamalek | - | Al Masry Club | 2:1 | ||||
| 17. Round | 01/05/2022 | Al Masry Club | - | Al Mokawloon | 0:2 |
Egypt