| 3. Round | 28/09/2020 | AE Lárissa | - | Panathinaikos | 1:1 | ||||
| 4. Round | 04/10/2020 | Panathinaikos | - | Aris Saloniki | 0:1 | ||||
| 6. Round | 24/10/2020 | Panathinaikos | - | Volos NFC | 1:1 | ||||
| 2. Round | 03/11/2020 | Panathinaikos | - | Apollon Smyrnis | 1:0 | ||||
| 8. Round | 07/11/2020 | Panathinaikos | - | Atromitos | 0:1 | ||||
| 10. Round | 29/11/2020 | Panathinaikos | - | Panetolikos | 2:1 | ||||
| 12. Round | 12/12/2020 | Panathinaikos | - | PAS Giannina | 2:0 |  |
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| 13. Round | 20/12/2020 | PAOK Saloniki | - | Panathinaikos | 2:1 | |
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| 14. Round | 03/01/2021 | Panathinaikos | - | Asteras Tripolis | 0:0 | ||||
| 15. Round | 06/01/2021 | Apollon Smyrnis | - | Panathinaikos | 0:1 | ||||
| 16. Round | 10/01/2021 | Panathinaikos | - | AE Lárissa | 2:0 | ||||
| 18. Round | 23/01/2021 | Panathinaikos | - | OFI Heraklion | 2:0 | |
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| 19. Round | 27/01/2021 | Volos NFC | - | Panathinaikos | 0:2 | ||||
| 20. Round | 30/01/2021 | Panathinaikos | - | Lamia | 0:0 | ||||
| 22. Round | 14/02/2021 | Panathinaikos | - | Olympiakos Piraeus | 2:1 | ||||
| 23. Round | 22/02/2021 | Panetolikos | - | Panathinaikos | 1:0 | ||||
| 25. Round | 06/03/2021 | PAS Giannina | - | Panathinaikos | 1:0 |
Spain