| 1. Round | 29/07/2017 | KAS Eupen | - | SV Zulte Waregem | 0:5 |  |
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| 2. Round | 06/08/2017 | Club Brugge KV | - | KAS Eupen | 3:1 | ||||
| 6. Round | 09/09/2017 | Waasland-Beveren | - | KAS Eupen | 5:1 | ||||
| 7. Round | 17/09/2017 | KAS Eupen | - | Standard Liège | 1:1 | ||||
| 8. Round | 23/09/2017 | Royal Excel Mouscron | - | KAS Eupen | 3:2 | ||||
| 9. Round | 30/09/2017 | KAS Eupen | - | KRC Genk | 3:3 |  |
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| 10. Round | 14/10/2017 | Sporting Charleroi | - | KAS Eupen | 2:2 | ||||
| 11. Round | 21/10/2017 | KAS Eupen | - | KV Mechelen | 4:1 | |
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| 12. Round | 24/10/2017 | KAA Gent | - | KAS Eupen | 3:0 | ||||
| 13. Round | 28/10/2017 | KAS Eupen | - | RSC Anderlecht | 2:3 | ||||
| 14. Round | 04/11/2017 | Sint-Truidense VV | - | KAS Eupen | 4:4 | |
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| 15. Round | 18/11/2017 | KAS Eupen | - | Royal Antwerp FC | 0:1 | ||||
| 16. Round | 25/11/2017 | KV Oostende | - | KAS Eupen | 1:0 | ||||
| 17. Round | 03/12/2017 | KAS Eupen | - | Club Brugge KV | 2:2 | |
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| 18. Round | 09/12/2017 | KRC Genk | - | KAS Eupen | 1:1 | |
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