| 1. Round | 08/08/2015 | Union Saint-Gilloise | - | KAS Eupen | 0:1 |  |
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| 2. Round | 12/08/2015 | KAS Eupen | - | KMSK Deinze | 5:1 | ||||
| 3. Round | 30/08/2015 | KVV Coxyde | - | KAS Eupen | 0:2 | ||||
| 5. Round | 13/09/2015 | KAS Eupen | - | Lierse SK (old) | 1:4 | |
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| 12. Round | 24/10/2015 | KSV Roeselare | - | KAS Eupen | 2:2 | ||||
| 18. Round | 04/12/2015 | KAS Eupen | - | Union Saint-Gilloise | 0:0 | ||||
| 19. Round | 12/12/2015 | KMSK Deinze | - | KAS Eupen | 1:1 | ||||
| 25. Round | 13/02/2016 | KAS Eupen | - | KSK Heist | 3:1 | ||||
| 26. Round | 21/02/2016 | Patro Eisden MM | - | KAS Eupen | 1:2 | ||||
| 27. Round | 06/03/2016 | KAS Eupen | - | Cercle Brugge | 2:1 |  |
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| 28. Round | 12/03/2016 | RFC Seraing | - | KAS Eupen | 0:3 | |
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| 29. Round | 18/03/2016 | KAS Eupen | - | KSV Roeselare | 4:0 | |
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| 30. Round | 02/04/2016 | Lommel United | - | KAS Eupen | 0:3 | ||||
| 31. Round | 09/04/2016 | KAS Eupen | - | Excelsior Virton | 2:1 | |
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| 32. Round | 15/04/2016 | AFC Tubize | - | KAS Eupen | 1:1 | ||||
| 34. Round | 30/04/2016 | Royal Antwerp FC | - | KAS Eupen | 0:0 |
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