| 1. Round | 15/08/2022 | FC Cartagena | - | SD Ponferradina | 2:3 | ||||
| 2. Round | 22/08/2022 | SD Ponferradina | - | UD Ibiza | 2:1 | ||||
| 3. Round | 28/08/2022 | SD Eibar | - | SD Ponferradina | 1:0 | ||||
| 4. Round | 03/09/2022 | SD Ponferradina | - | Sporting Gijón | 1:3 | ||||
| 7. Round | 24/09/2022 | SD Ponferradina | - | CD Tenerife | 2:2 |  |
|||
| 10. Round | 12/10/2022 | Villarreal CF B | - | SD Ponferradina | 2:2 | ||||
| 13. Round | 29/10/2022 | FC Andorra | - | SD Ponferradina | 3:0 | ||||
| 15. Round | 05/11/2022 | CD Leganés | - | SD Ponferradina | 2:1 |
Portugal