| 15. Round | 25/01/2022 | US Biskra | - | Olympique Médéa | 2:1 | ||||
| 20. Round | 05/03/2022 | RC Rélizane | - | US Biskra | 1:1 | ||||
| 21. Round | 11/03/2022 | US Biskra | - | USM Alger | 0:0 |  |
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| 24. Round | 01/04/2022 | ASO Chlef | - | US Biskra | 2:0 | ||||
| 25. Round | 13/04/2022 | US Biskra | - | MC Oran | 2:2 | ||||
| 27. Round | 22/04/2022 | US Biskra | - | NC Magra | 1:0 | ||||
| 26. Round | 31/05/2022 | CR Bélouizdad | - | US Biskra | 2:0 | ||||
| 33. Round | 05/06/2022 | US Biskra | - | ES Sétif | 1:1 | ||||
| 34. Round | 10/06/2022 | NA Hussein Dey | - | US Biskra | 1:2 |
Algeria