| 1. Round | 30/07/2016 | FK Rostov | - | FK Orenburg | 1:0 | ||||
| 2. Round | 07/08/2016 | FK Orenburg | - | CSKA Moskva | 0:1 | ||||
| 8. Round | 25/09/2016 | FK Orenburg | - | FK Ural | 0:1 | ||||
| 9. Round | 01/10/2016 | Terek Grozny | - | FK Orenburg | 2:1 | ||||
| 10. Round | 16/10/2016 | FK Orenburg | - | FK Tom Tomsk | 3:1 | ||||
| 11. Round | 24/10/2016 | Zenit St. Petersburg | - | FK Orenburg | 1:0 | ||||
| 12. Round | 31/10/2016 | FK Orenburg | - | Krylia Sovetov | 1:0 |  |
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| 13. Round | 06/11/2016 | FK Krasnodar | - | FK Orenburg | 3:3 | |
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| 14. Round | 19/11/2016 | FK Orenburg | - | Lokomotiv Moskva | 1:1 | ||||
| 15. Round | 25/11/2016 | FK Ufa | - | FK Orenburg | 1:0 | ||||
| 16. Round | 30/11/2016 | CSKA Moskva | - | FK Orenburg | 2:0 | ||||
| 17. Round | 05/12/2016 | FK Amkar Perm | - | FK Orenburg | 3:0 |
Belarus