| 1. Round | 20/09/2020 | Sliema Wanderers | - | Hibernians FC | 3:1 | ||||
| 2. Round | 25/09/2020 | Sirens FC | - | Sliema Wanderers | 0:0 | ||||
| 3. Round | 01/10/2020 | Sliema Wanderers | - | St. Luċija FC | 3:1 |  |
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| 7. Round | 01/11/2020 | Sliema Wanderers | - | Balzan FC | 3:1 | |
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| 8. Round | 21/11/2020 | Gżira United | - | Sliema Wanderers | 3:2 | ||||
| 9. Round | 28/11/2020 | Sliema Wanderers | - | Lija Athletics FC | 4:1 | ||||
| 10. Round | 05/12/2020 | Zejtun Corinthians | - | Sliema Wanderers | 2:4 | ||||
| 12. Round | 13/12/2020 | Floriana FC | - | Sliema Wanderers | 0:1 | ||||
| 13. Round | 18/12/2020 | Tarxien Rainbows | - | Sliema Wanderers | 1:2 |  |
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| 14. Round | 06/01/2021 | Sliema Wanderers | - | Mosta FC | 1:3 | ||||
| 16. Round | 16/01/2021 | Hibernians FC | - | Sliema Wanderers | 1:0 | |
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| 17. Round | 23/01/2021 | Sliema Wanderers | - | Sirens FC | 1:3 | ||||
| 18. Round | 29/01/2021 | St. Luċija FC | - | Sliema Wanderers | 0:1 | ||||
| 15. Round | 03/02/2021 | Valletta FC | - | Sliema Wanderers | 0:0 | |
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| 19. Round | 06/02/2021 | Sliema Wanderers | - | Senglea Athletics | 3:1 | ||||
| 21. Round | 20/02/2021 | Sliema Wanderers | - | Birkirkara FC | 2:2 | |
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| 23. Round | 06/03/2021 | Sliema Wanderers | - | Gżira United | 2:0 |
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