| 1. Round | 20/09/2020 | Floriana FC | - | Gżira United | 2:1 | ||||
| 2. Round | 27/09/2020 | Hibernians FC | - | Floriana FC | 3:1 | ||||
| 3. Round | 01/10/2020 | Floriana FC | - | Sirens FC | 3:2 | ||||
| 4. Round | 16/10/2020 | St. Luċija FC | - | Floriana FC | 2:1 | ||||
| 5. Round | 21/10/2020 | Floriana FC | - | Senglea Athletics | 1:0 | ||||
| 6. Round | 25/10/2020 | Gudja United | - | Floriana FC | 1:2 | ||||
| 10. Round | 06/12/2020 | Valletta FC | - | Floriana FC | 0:3 | ||||
| 12. Round | 13/12/2020 | Floriana FC | - | Sliema Wanderers | 0:1 | ||||
| 13. Round | 19/12/2020 | Hamrun Spartans | - | Floriana FC | 3:1 | ||||
| 7. Round | 22/12/2020 | Floriana FC | - | Birkirkara FC | 2:5 | ||||
| 15. Round | 10/01/2021 | Floriana FC | - | Zejtun Corinthians | 0:0 | ||||
| 11. Round | 13/01/2021 | Tarxien Rainbows | - | Floriana FC | 2:2 | ||||
| 16. Round | 16/01/2021 | Gżira United | - | Floriana FC | 4:1 | ||||
| 14. Round | 27/01/2021 | Floriana FC | - | Lija Athletics FC | 1:2 |  |
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| 20. Round | 13/02/2021 | Senglea Athletics | - | Floriana FC | 0:2 | ||||
| 22. Round | 27/02/2021 | Birkirkara FC | - | Floriana FC | 2:0 | ||||
| 23. Round | 06/03/2021 | Floriana FC | - | Balzan FC | 0:0 |
Malta