| 19. Round | 03/08/2018 | Bhayangkara Surabaya United F.C | - | PSMS Medan (ISL) | 3:1 | ||||
| 20. Round | 12/08/2018 | Persija Jakarta | - | PSMS Medan (ISL) | 0:0 | ||||
| 21. Round | 12/09/2018 | PSMS Medan (ISL) | - | PSIS Semarang | 2:3 | ||||
| 22. Round | 16/09/2018 | Perseru Serui | - | PSMS Medan (ISL) | 1:1 |  |
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| 23. Round | 21/09/2018 | PSMS Medan (ISL) | - | Persela Lamongan | 3:2 |  |
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| 24. Round | 07/10/2018 | PS Barito Putera | - | PSMS Medan (ISL) | 3:3 | |
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| 26. Round | 18/10/2018 | Sriwijaya FC | - | PSMS Medan (ISL) | 0:3 | |
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| 27. Round | 23/10/2018 | PSMS Medan (ISL) | - | Mitra Kukar | 1:3 | ||||
| 28. Round | 28/10/2018 | Arema Cronus FC | - | PSMS Medan (ISL) | 5:0 | ||||
| 29. Round | 03/11/2018 | PSMS Medan (ISL) | - | Pusamania Borneo F.C. | 3:2 | ||||
| 30. Round | 09/11/2018 | Persib Bandung | - | PSMS Medan (ISL) | 0:1 | ||||
| 31. Round | 17/11/2018 | PSMS Medan (ISL) | - | Madura United | 3:3 | |
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| 33. Round | 01/12/2018 | PSMS Medan (ISL) | - | Persebaya Surabaya | 4:0 | ||||
| 25. Round | 05/12/2018 | PSMS Medan (ISL) | - | PS-TIRA | 2:4 | |
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| 34. Round | 09/12/2018 | PSM Makassar | - | PSMS Medan (ISL) | 5:1 |
Germany