1. Round | 16/01/2022 | Once Municipal | - | FAS | 1:1 | ||||
3. Round | 26/01/2022 | Once Municipal | - | Municipal Limeño | 3:2 | ||||
4. Round | 30/01/2022 | Atlético Marte | - | Once Municipal | 1:1 | ||||
10. Round | 27/02/2022 | Once Municipal | - | CD Águila | 1:4 | ||||
11. Round | 05/03/2022 | Jocoro FC | - | Once Municipal | 2:1 | ||||
12. Round | 13/03/2022 | FAS | - | Once Municipal | 0:0 | ||||
13. Round | 19/03/2022 | Once Municipal | - | Santa Tecla FC | 1:0 | ||||
14. Round | 25/03/2022 | Municipal Limeño | - | Once Municipal | 0:0 | ||||
15. Round | 03/04/2022 | Once Municipal | - | Atlético Marte | 1:0 | ||||
16. Round | 10/04/2022 | Isidro Metapán | - | Once Municipal | 2:2 | ||||
18. Round | 17/04/2022 | Luis Ángel Firpo | - | Once Municipal | 0:0 |