| 1. Round | 03/09/2021 | Persikabo 1973 | - | Madura United | 1:1 | ||||
| 2. Round | 12/09/2021 | Madura United | - | PSM Makassar | 1:1 | ||||
| 4. Round | 25/09/2021 | Madura United | - | PSS Sleman | 1:0 | ||||
| 5. Round | 29/09/2021 | PSIS Semarang | - | Madura United | 0:0 |  |
|||
| 7. Round | 16/10/2021 | Persela Lamongan | - | Madura United | 2:2 |  |
|||
| 8. Round | 22/10/2021 | Madura United | - | Persija Jakarta | 2:3 | ||||
| 9. Round | 27/10/2021 | Persiraja Banda Aceh | - | Madura United | 1:2 | ||||
| 10. Round | 01/11/2021 | Madura United | - | Arema Cronus FC | 1:2 | ||||
| 11. Round | 06/11/2021 | Madura United | - | Persita Tangerang | 1:2 | ||||
| 12. Round | 20/11/2021 | Persebaya Surabaya | - | Madura United | 1:0 | ||||
| 15. Round | 04/12/2021 | Madura United | - | Persib Bandung | 0:1 |
Indonesia