| 1. Round | 02/08/2020 | Real Estelí FC | - | Club Deportivo Ocotal | 2:1 | ||||
| 4. Round | 16/08/2020 | Chinandega | - | Club Deportivo Ocotal | 4:2 | ||||
| 5. Round | 24/08/2020 | Club Deportivo Ocotal | - | Real Madriz | 1:1 | ||||
| 6. Round | 31/08/2020 | Juventus Managua | - | Club Deportivo Ocotal | 1:0 | ||||
| 7. Round | 07/09/2020 | Club Deportivo Ocotal | - | ART Municipal Jalapa | 0:0 | ||||
| 8. Round | 13/09/2020 | CD Walter Ferretti | - | Club Deportivo Ocotal | 2:0 | ||||
| 11. Round | 01/10/2020 | Managua FC | - | Club Deportivo Ocotal | 2:2 | ||||
| 14. Round | 30/10/2020 | Real Madriz | - | Club Deportivo Ocotal | 0:1 | ||||
| 16. Round | 12/11/2020 | ART Municipal Jalapa | - | Club Deportivo Ocotal | 2:0 |  |
Honduras