| 1. Round | 11/07/2022 | Deportes Tolima | - | Independiente Medellín | 1:1 | ||||
| 2. Round | 15/07/2022 | Deportes Tolima | - | Deportivo Cali | 2:0 | ||||
| 3. Round | 19/07/2022 | Unión Magdalena | - | Deportes Tolima | 2:1 |  |
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| 4. Round | 24/07/2022 | Deportes Tolima | - | Atlético Nacional | 2:2 | ||||
| 5. Round | 02/08/2022 | Atlético Bucaramanga | - | Deportes Tolima | 2:1 |
Colombia