| 6. Round | 03/01/2021 | Club Africain | - | ES Métlaoui | 0:1 | ||||
| 7. Round | 09/01/2021 | CA Bizertin | - | Club Africain | 1:1 | ||||
| 8. Round | 12/01/2021 | Club Africain | - | Étoile du Sahel | 1:1 | ||||
| 9. Round | 24/01/2021 | AS Soliman | - | Club Africain | 2:1 | ||||
| 10. Round | 27/01/2021 | Club Africain | - | US Monastir | 1:3 | ||||
| 17. Round | 10/03/2021 | US Tataouine | - | Club Africain | 0:0 | ||||
| 18. Round | 14/03/2021 | Club Africain | - | US Ben Guerdane | 1:0 | ||||
| 22. Round | 04/04/2021 | Club Africain | - | AS Soliman | 2:1 |
Tunisia