| 1. Round | 27/10/2021 | Ismaily | - | Al Ahly SC | 0:4 |  |
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| 2. Round | 31/10/2021 | Al Ahly SC | - | National Bank SC | 1:0 | ||||
| 3. Round | 05/11/2021 | Zamalek | - | Al Ahly SC | 3:5 | ||||
| 4. Round | 19/11/2021 | Al Ahly SC | - | Al Mokawloon | 1:0 | ||||
| 5. Round | 22/11/2021 | Ghazl Al Mehalla | - | Al Ahly SC | 2:3 | |
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| 10. Round | 22/02/2022 | Al Ahly SC | - | Misr lel-Maqasah SC | 4:0 | ||||
| 11. Round | 01/03/2022 | Pharco FC | - | Al Ahly SC | 1:4 | ||||
| 8. Round | 08/03/2022 | Al Ahly SC | - | Pyramids FC | 3:0 |  |
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| 12. Round | 06/04/2022 | Al Ahly SC | - | Ittihad El Iskandary | 1:0 | ||||
| 13. Round | 09/04/2022 | Al Masry Club | - | Al Ahly SC | 1:0 | ||||
| 16. Round | 27/04/2022 | Al Ahly SC | - | Tala'ea El Gaish SC | 0:0 | ||||
| 20. Round | 19/06/2022 | Al Ahly SC | - | Zamalek | 2:2 | ||||
| 22. Round | 22/06/2022 | Al Ahly SC | - | Ghazl Al Mehalla | 2:1 | ||||
| 9. Round | 05/07/2022 | El Gouna | - | Al Ahly SC | 0:0 | ||||
| 24. Round | 12/07/2022 | Al Ahly SC | - | Future FC | 4:0 | ||||
| 25. Round | 16/07/2022 | Pyramids FC | - | Al Ahly SC | 2:0 | ||||
| 26. Round | 24/07/2022 | Al Ahly SC | - | El Gouna | 2:0 | |
Egypt