| 2. Round | 12/09/2021 | Persija Jakarta | - | PSIS Semarang | 2:2 | ||||
| 3. Round | 18/09/2021 | PSIS Semarang | - | Persiraja Banda Aceh | 3:1 | ||||
| 7. Round | 15/10/2021 | PSIS Semarang | - | Persik Kediri | 3:0 |  |
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| 8. Round | 20/10/2021 | PS Barito Putera | - | PSIS Semarang | 0:1 | ||||
| 9. Round | 26/10/2021 | PSIS Semarang | - | Persib Bandung | 0:1 | ||||
| 10. Round | 31/10/2021 | Bali United | - | PSIS Semarang | 0:0 | ||||
| 11. Round | 06/11/2021 | PSIS Semarang | - | Borneo FC | 0:1 | ||||
| 14. Round | 26/11/2021 | Bhayangkara Presisi Indonesia | - | PSIS Semarang | 0:0 | ||||
| 15. Round | 03/12/2021 | PSIS Semarang | - | PSS Sleman | 1:2 | ||||
| 28. Round | 28/02/2022 | PSIS Semarang | - | Persikabo 1973 | 1:0 | ||||
| 30. Round | 12/03/2022 | PSIS Semarang | - | Bhayangkara Presisi Indonesia | 1:1 | ||||
| 34. Round | 29/03/2022 | Persela Lamongan | - | PSIS Semarang | 1:2 |
Indonesia