| 1. Round | 06/08/2005 | San Lorenzo | - | Vélez Sarsfield | 3:2 |  |
|||
| 2. Round | 14/08/2005 | Estudiantes | - | San Lorenzo | 0:1 | ||||
| 3. Round | 21/08/2005 | San Lorenzo | - | Independiente | 1:1 | ||||
| 15. Round | 17/11/2005 | River Plate | - | San Lorenzo | 5:1 | |
|||
| 16. Round | 22/11/2005 | San Lorenzo | - | Newell's Old Boys | 4:2 | |
|||
| 17. Round | 25/11/2005 | Banfield | - | San Lorenzo | 5:0 | ||||
| 18. Round | 04/12/2005 | San Lorenzo | - | Colón de Santa Fe | 1:4 | |
|||
| 19. Round | 11/12/2005 | Arsenal de Sarandí | - | San Lorenzo | 1:2 |
Colombia